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Will MSM Ease Pain and Swelling in Arthritic Joints?

NSAIDs can help ease swollen, painful joints, but they have drawbacks. MSM might offer an alternative to treat arthritis pain.

Arthritis frequently puts people in a terrible double-bind. The medications that are generally used to ease the pain of stiff joints can have risky side effects. People often rely on over-the-counter NSAIDs (nonsteroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin) or naproxen (Aleve). Unfortunately, like their prescription counterparts such as diclofenac, these drugs can raise blood pressure, increase the risk of cardiovascular complications and damage the intestinal tract. Might MSM be a viable alternative?

 One Reader Tries MSM for Sore Thumbs:

Q. I have had arthritis for years and had been taking diclofenac; however, my doctor took me off of it because it started to affect my kidneys. When the joints in my thumbs started to swell so I couldn’t even open a soft drink bottle, I started looking for some help.

Lucky for me, I found MSM. After taking it for three days, the swelling in my thumbs went down.

It’s been a few months and I am now able to walk three miles a day and have had other positive results. For example, my hair and my nails have improved. I know that this won’t cure arthritis, but it seems to have slowed its progression.

What Is MSM?

A. MSM (methylsulfonylmethane) is a natural compound that is marketed as a dietary supplement. There is limited research on its use for arthritis. A recent review indicates that it may be of benefit (Mayo Clinic Proceedings, Sept., 2016).  Another study found that MSM combined with the herb boswellia was helpful in treating knee arthritis (International Journal of Immunopathology and Pharmacology, March, 2016).

If you are interested in other approaches for easing painful joints, you might wish to consult our Guide to Alternatives for Arthritis.

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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies..
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