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Will Garlic Supplements Lower Your Blood Pressure?

Garlic has a long history as a medicinal food. Research shows that garlic supplements lower your blood pressure about as well as antihypertensive medicines.

Garlic is a foundational flavor in many cuisines. People around the world also use garlic medicinally. It has long held a reputation for being able to help fight off infections, from colds and flu to tuberculosis. Many enthusiasts also believe that this allium vegetable also has anti-cancer activity. Could taking garlic supplements lower your blood pressure as well?

Do Garlic Supplements Work Like Raw Garlic?

Q. I have read that people who eat garlic live longer, in part because it helps lower blood pressure and triglycerides. I hate the smell of garlic. Would a garlic supplement offer the same protection?

Different Types of Garlic Supplements:

A. There are many types of garlic supplements, and they may act somewhat differently in the body. However, researchers have found that garlic extract can improve blood vessel flexibility and reduce inflammation and cholesterol more than placebo (Biomedicine & Pharmacotherapy, June 2018). Another randomized, placebo-controlled trial found that aged garlic extract lowered markers of inflammation and immune excitation (Clinical Nutrition ESPEN, April 2018). 

Garlic Supplements Lower Your Blood Pressure:

Garlic extract appears to offer at least some of the benefits of fresh garlic in lowering blood pressure, blood lipids and blood sugar (Neurological Research, June 2018).  The sulfur-containing compounds in garlic that give it a distinctive odor can also release hydrogen sulfide in the body, with benefits for both the cardiovascular system and immune response (Nutrients, Jan. 30, 2019). This suggests that garlic extracts or supplements should also contain sulfur compounds. A double-blind controlled trial (the GarGIC) study found that people who took Kyolic aged garlic extract for three months lowered their blood pressure about as much as if they had taken standard antihypertensive drugs (Frontiers in Nutrition, Dec. 11, 2018). That amounts to roughly 10 mm Hg systolic and more than 5 mm Hg diastolic.

Can Garlic Extract Help the Brain?

An intriguing study published in the journal Preventive Nutrition and Food Science (June 30, 2019) suggests that aged garlic extract may also help protect the brain.  Researchers gave mice the drug scopolamine to mimic Alzheimer’s disease. Black garlic extract blocked the cognitive impairment scopolamine would have caused. Whether this will provide any benefit to humans with aging brains remains to be determined.

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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies..
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Citations
  • Szulińska M et al, "Garlic extract favorably modifies markers of endothelial function in obese patients -randomized double blind placebo-controlled nutritional intervention." Biomedicine & Pharmacotherapy, June 2018. DOI: 10.1016/j.biopha.2018.03.131
  • Xu C et al, "Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity: A randomized, double-blind, placebo-controlled clinical trial." Clinical Nutrition ESPEN, April 2018. DOI: 10.1016/j.clnesp.2017.11.010
  • Zhu Y et al, "A mini review: garlic extract and vascular diseases." Neurological Research, June 2018. DOI: 10.1080/01616412.2018.1451269
  • Rodrigues C & Percival SS, "Immunomodulatory effects of glutathione, garlic derivatives, and hydrogen sulfide." Nutrients, Jan. 30, 2019. DOI: 10.3390/nu11020295
  • Ried K et al, "The effect of Kyolic aged garlic extract on gut microbiota, inflammation, and cardiovascular markers in hypertensives: The GarGIC trial." Frontiers in Nutrition, Dec. 11, 2018. DOI: 10.3389/fnut.2018.00122
  • Li F & Kim MY, "Effect of aged garlic ethyl acetate extract on oxidative stress and cholinergic function of scopolamine-induced cognitive impairment in mice." Preventive Nutrition and Food Science, June 30, 2019. doi: 10.3746/pnf.2019.24.2.165
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