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What Are the Unexpected Risks of Short-Term Steroid Use?

Even short-term steroid use can increase a person's chance of breaking a bone, developing a severe infection or having a bad blood clot.

Corticosteroids such as methylprednisolone or prednisone are powerful anti-inflammatory medications. Doctors frequently prescribe these medications for bronchitis, sinusitis, asthma, allergic reactions and backache. They may also treat a bad case of poison ivy or a flare-up of rheumatoid arthritis with short-term steroid use.

Are There Risks from Short-Term Steroid Use?

Most doctors are well aware of the dangers of long-term oral steroids. These drugs can increase the risk of diabetes, high blood pressure and osteoporosis. People taking such medications for months or years are more vulnerable to infections and dangerous blood clots. Some patients may develop psychological reactions.

Many prescribers assume that short-term steroid use carries minimal risk. A new study utilizing insurance information on 1.5 million adults found some unexpected complications of oral steroids taken for less than a month. Often, when these drugs are prescribed for a short period of time, patients start with a high dose and taper down over several days or a few weeks. People who were taking inhaled steroids for asthma, COPD or allergies were not included in the data analysis for this study.

The Hazards of Short-Term Steroids:

People who took these medications even short term were more likely to break a bone, develop a blood clot or come down with a serious infection (sepsis). These risks started immediately and lasted for at least three months. Such data suggest that everyone should become aware of the potential side effects of medications like prednisone.

Waljee et al, BMJ, April 12, 2017

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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies..
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