The larger a man’s prostate, the higher his PSA might be. That could easily lead to a biopsy and diagnosis of prostate cancer. A new study suggests that a larger prostate may be associated with less severe prostate cancer. The scientists reviewed 1,250 cases of prostate cancer. All the men had their prostates surgically removed although they were considered low-risk. But pathological examination of the tissue after surgery resulted in one-third of the cases being reclassified at higher risk. Men with smaller prostate glands were more likely to have a more aggressive form of cancer.