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News of Trouble with Reflux Drugs

Acid suppressing drugs have become among the most frequently prescribed pills in the pharmacy. Over 100 million prescriptions are filled for medications such as Aciphex, Nexium and Protonix. Prilosec and Prevacid are now also available over the counter. Given their popularity you might think that these medicines would have few, if any side effects.

But new studies show that proton pump inhibitors increase the risk of recurrent digestive tract infections caused by the bacteria called Clostridium difficile, or C diff. This type of infection causes diarrhea that can sometimes be lethal.

PPI acid-suppressing drugs can also increase the risk of broken bones in postmenopausal women. In this study, nearly 162,000 women were tracked for eight years. Those who took PPIs were at a slightly increased risk for spine or wrist fractures. Perhaps it’s time to reevaluate the routine use of acid suppressing drugs for heartburn.

[Archives of Internal Medicine, May 10, 2010]

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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies..
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