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Muscle and Memory Problems with Cholesterol-Lowering Drugs

Q. I have read that Lipitor may cause memory impairment. I am taking Lipitor and am having trouble with speaking and memory along with intense muscle soreness. My lab tests are within the normal range so my doctor says Lipitor is not the source of my problems.

Are there other drugs without these side effects?  A friend mentioned red yeast rice. Do you have any information about it?

A. A study of statin-type cholesterol-lowering drugs (such as Crestor, Lipitor or simvastatin) revealed that that these drugs can cause structural muscle damage. Normal blood tests (creatine phosphokinase) don’t rule out serious muscle injury (Canadian Medical Association Journal, July 7, 2009). Memory loss and amnesia have occasionally been reported as side effects with statins.

Red yeast rice is a dietary supplement that has centuries of use in traditional Chinese cooking and medicine. One recent study suggests that some people who have difficulty with statins can lower their cholesterol with red yeast rice (Annals of Internal Medicine, June 16, 2009). Others may find, though, that it causes similar side effects to statins.

We are sending you our Guide to Cholesterol Control and Heart Health for the pros and cons of statins and more details about red yeast rice and other ways to lower cholesterol. 

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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies..
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