Memory Problems Because of Low Vitamin B12 Levels

Q. My husband’s memory has been getting hazy, and I am concerned. He was tested by a neurologist who found that his vitamin B12 level was low. Shots were recommended, but that was difficult for us, and our internist suggested Nascobal nose drops as an alternative.
We’ve had some trouble with this product. To my way of thinking, the dropper is hard to use. Is there any other way for him to get this vitamin?

A. Vitamin B12 deficiency can lead to neurological symptoms such as moodiness, difficulty concentrating, memory loss, unsteadiness, numbness and tingling in hands and feet. It is very important for you and your husband to try to find out why his vitamin B12 levels are low. There are medications that can lead to this complication.
In our brand new book, Top Screwups Doctors Make and How to Avoid Them we have a whole section on drugs that can cause fuzzy thinking, mental confusion and forgetfulness. These are medications that can deplete the body of vitamin B12 or drugs that have what is referred to as anticholinergic action. That means they interfere with the brain chemical acetylcholine, which is essential for proper neurological functioning. Find out more in our brand new book and take advantage of the early bird discount price.
The usual solution to this vitamin deficiency is a monthly B12 shot. There are other alternatives, however.
Nasal gels such as Nascobal or Ener-B are one approach. The other possibilities are high-dose oral pills daily (1 to 2 mg) or “nuggets” designed to dissolve under the tongue. Ask the doctor to review the research in Blood (volume 92; August 15, 1998; pages 1191-1198).
No matter what, it will be essential for your husband to have his blood monitored carefully to make sure the deficiency has been corrected. Once you have discovered why your husband has a vitamin B12 deficiency, it may be possible to correct this imbalance without continued use of supplements.