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Low Vitamin D Linked to Cognitive Decline

Seniors with low vitamin D blood levels are at greater risk for dementia or memory loss. Would supplements help? We don't know.

Low vitamin D levels could be bad for your brain, especially as you age.

Who Participated in the Study:

Researchers tracked cognitive function and memory in 318 older adults over a time frame of about five years. Their average age was 75, and roughly half had some degree of cognitive impairment at the start of the study. They were from a variety of ethnic groups.

The Impact of Low Vitamin D:

The scientists also measured blood levels of 25-hydroxyvitamin D, a measure of vitamin D status in the body. Roughly 25 percent of the subjects in the study were deficient in vitamin D, meaning that their levels of 25-hydroxyvitamin D were below 12 ng/mL.

More than half of the volunteers had low vitamin D levels. The lower the levels of vitamin D, the greater the decline in both memory and cognitive function over the five-year assessment period.

The Take-Home Message:

The authors conclude that low vitamin D levels may correspond to an elevated risk for dementia. Since so many seniors stay out of the sun and have low vitamin D levels, this is a significant concern.

What is unknown, however, is whether taking vitamin D supplements could prevent or slow mental decline. Anyone who decides to try supplements should be sure to take vitamin D3 along with a meal that contains a certain amount of fat. (We have written about that here.)

JAMA Neurology, online, September 14, 2015

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About the Author
Joe Graedon is a pharmacologist who has dedicated his career to making drug information understandable to consumers. His best-selling book, The People’s Pharmacy, was published in 1976 and led to a syndicated newspaper column, syndicated public radio show and web site. In 2006, Long Island University awarded him an honorary doctorate as “one of the country's leading drug experts for the consumer.”.
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