A new study suggests that low-dose aspirin may not protect the heart as well as expected. Comparing blood pressure between the ankle and the arm provides a marker for the risk of future cardiovascular complications. A randomized controlled trial was carried out in Scotland on more than 3,000 men and women over 50. These people had been selected from more than 29,000 adults because they were healthy but at high risk. There was no significant difference in heart attacks, other vascular problems or death between those who took 100 mg of aspirin daily and those who took placebo. The patients were followed for an average of 8 years. Although this study throws doubt on aspirin’s value for preventing heart attacks, patients who have been told to take this drug should discuss it with their doctors and not stop it on their own.
[JAMA, March 3, 2010]