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Getting Off Antidepressant Can Be Difficult

Q. I have been taking Effexor XR for two years. At first I was pleased that it relieved the anxiety, depression and excessive worrying I had been suffering. Then I began experiencing insomnia and night sweats and decided to taper off this antidepressant.

After cutting my dose in half I have brain zaps (impossible to explain) and pressure in my ears. It is truly a hellish experience. Most doctors don’t warn you about withdrawal or tell you how to get off these drugs. Do you have any information that will help?

A. Many people find that antidepressants such as Effexor (venlafaxine), Cymbalta (duloxetine), Lexapro (escitalopram), Paxil (paroxetine) or Zoloft (sertraline) are helpful for depression. But there can be a dark side to such medications.

Stopping this type of drug may lead to withdrawal symptoms that are extremely disruptive. Symptoms may include dizziness, headaches, insomnia, anxiety, sweating, visual disturbances and difficulty concentrating. Many people complain of shock-like sensations in their head (brain “zaps” or “shivers”).

We are sending you our Guide to Dealing with Depression with some tips on phasing off such drugs and some alternate approaches for coping.

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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies..
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