Q. How dangerous is Arthrotec? I have been taking it for more than five years but I am getting leery. I read that it might lead to bleeding ulcers that can cause death. Is there anything else I can take for arthritis in my knees and hands?
A. Arthrotec combines a prescription nonsteroidal anti-inflammatory drug (NSAID) called diclofenac with a medication to prevent ulcers called misoprostol. Even with this protective medication, though, there is no guarantee that the NSAID will not lead to bleeding ulcers. Other complications of such drugs include increases in blood pressure and an increased risk of heart attacks or strokes.
Similar arthritis drugs that are prescribed or taken over the counter are no safer than Arthrotec and may be more likely to lead to ulceration. One way to reduce this risk is to use a drug that is applied to the skin, such as Voltaren Gel.
We are sending you our Guide to Alternatives for Arthritis so that you can learn more about such topical NSAIDs, other medications less likely to cause ulcers and nondrug approaches.
