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Drug May Provoke Painful Nighttime Erections

Q. During sleep I am awakened five or six times a night by erections. I’m 53 years old and take Flomax, venlafaxine, fosinopril, trazodone and vitamin B12. Can any of these medications cause this problem?

A. Men frequently experience erections during rapid eye movement (REM) sleep. This is normally when dreams occur. The erections have nothing to do with the content of the dreams but are a physiological reaction to this stage of sleep.

The antidepressant trazodone (Desyrel) has been linked to prolonged painful erections (priapism). This can occur during sleep or even during the daytime.

Flomax can also trigger this reaction. Both drugs together might make matters worse. A prolonged erection can be damaging and requires medical intervention.

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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies..
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