Go Ad-Free
logoThe People's Perspective on Medicine

Drug for Restless Legs May Trigger Compulsive Gambling or Sexual Behavior

Q. I have endured restless legs syndrome (RLS) for years. I also suffer from extreme compulsive behavior, including shopping and gambling. I take Mirapex both evening and morning, as my RLS symptoms have become worse with age.

This medication has ruined my life. I only discovered recently that the compulsive behaviors are drug side effects.

A. Many people are surprised to learn that medicine taken for Parkinson’s disease or RLS is linked to bad behavior–gambling, hypersexuality or compulsive shopping. A reader reported that one of these, Requip (ropinirole), turned her into a big-time gambler. Another woman said this about Mirapex (pramipexole):

“I took Mirapex for a year. I was already taking Sinemet for Parkinson’s disease. I shopped compulsively, buying many things that I did not need. I filled closets with 
stuff, some of which I did not remember when I saw them later.

“Stopping Mirapex stopped the compulsive behavior. Not only was the drug itself expensive, I can only imagine how much it cost otherwise, in both money and health.”

Some readers have found that putting soap in socks can calm the restlessness that is so distressing. Although this is unlikely to be as effective as prescription medication, the remedy is also free of the devastating side effects you experienced.

Rate this article
star-fullstar-emptystar-fullstar-emptystar-fullstar-emptystar-fullstar-emptystar-fullstar-emptystar-fullstar-emptystar-fullstar-emptystar-fullstar-emptystar-fullstar-emptystar-fullstar-empty
4.3- 4 ratings
About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies..
Tired of the ads on our website?

Now you can browse our website completely ad-free for just $5 / month. Stay up to date on breaking health news and support our work without the distraction of advertisements.

Browse our website ad-free
Join over 150,000 Subscribers at The People's Pharmacy

We're empowering you to make wise decisions about your own health, by providing you with essential health information about both medical and alternative treatment options.