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Difficulties with Simvastatin

Q. I’ve been on simvastatin for about six months and I have developed excruciating hip and upper leg pain. I get very tired in the middle of the afternoon and sometimes go to bed by 8 PM.

I also am troubled with constipation, then the runs. I feel like I’m 100 years old though I am 69. Could simvastatin be causing all this trouble?

A. Statins such as atorvastatin (Lipitor), lovastatin, pravastatin, rosuvastatin (Crestor) and simvastatin may cause fatigue, digestive distress and muscle or joint pain. The discomfort can affect almost any part of the body including neck, back, legs or hips.

Muscle weakness may also affect the eyes. A recent report in The American Journal of Medicine (March, 2011) describes a man who had to stop driving because of red, irritated eyes and double vision caused by atorvastatin. The authors found 256 cases of statin-induced eye problems in medical reports.

We are sending you our Guide to Cholesterol Control and Heart Health, with pros and cons of statins and many alternatives for lowering blood lipids.

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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies..
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