Q. I cannot take statins, but my cholesterol is very high. My physician has recommended that I take cholestyramine. Can you tell me about the pros and cons of this drug?
A. Cholestyramine was approved under the brand name Questran in 1973. This compound absorbs bile acids and prevents the reabsorption of cholesterol from the digestive tract. It is an old-fashioned inexpensive approach that can lower bad LDL cholesterol. Because it works so differently from statins, you are unlikely to suffer muscle or nerve pain.
Some people may experience digestive tract upset such as constipation, flatulence or heartburn. Other reactions to watch out for are headache, fatigue and rash.
We are sending you our Guide to Cholesterol Control and Heart Health with many other suggestions for lowering blood lipids with and without prescription drugs.