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Bedtime Pill Could Raise Heat Risk

Q. I take amitriptyline at night to help me sleep. I have read that this drug might make me more sensitive to the heat. I have been really suffering with the temperatures hovering around 100 degrees. Could my sleeping pill be dangerous?

A. Amitriptyline is a sedating antidepressant. The FDA has not approved it for use as a sleeping pill although it is frequently prescribed for this purpose.

Because amitriptyline interferes with sweating, your body cannot dissipate extra heat as it normally would. This might put you at risk for heat stroke.

Stopping the drug suddenly might cause withdrawal symptoms, including insomnia. Please discuss this dilemma with your doctor.

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About the Author
Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Terry taught in the Duke University School of Nursing and was an adjunct assistant professor in the Department of Anthropology. She is a Fellow of the Society of Applied Anthropology. Terry is one of the country's leading authorities on the science behind folk remedies..
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