Our genes may predispose us to some health problems, and others are triggered by environmental toxins. But how do our genes affect our reactions to compounds in the air, water or food? Asthma is one example of a common disease in which both genes and toxins play a critical role. How do they interact? Guests: William A. Suk, PhD, MPH, Director of the Center for Risk and Integrated Sciences; and Director of the Superfund Basic Research Program at the National Institute of Environmental Health Sciences David Schwartz, MD, Professor of Medicine and Geriatrics; Director of the Pulmonary, Allergy and Critical Care Division; Director of the Program in Environmental Genomics in the Institute for Genome Science and Policy, Duke University